Neurotoxins

Merz is dedicated to the development of botulinum neurotoxin for therapeutic use; we are constantly working to advance new treatment standards and improve the quality of research, education and patient care within the movement disorders space.

For patients with movement disorders, botulinum neurotoxin is often the treatment of choice.

What is Botulinum Neurotoxin?

Botulinum neurotoxin is a very complex substance produced by bacteria. Botulinum neurotoxin attaches itself exclusively to nerve cells that activate the muscular system or specific glands – effectively and accurately blocking an overactive muscle or gland. The effect is reversible after a certain period of time (depending on dosage and injection location), so that repetition of the injection is typically necessary.

Every Patient is Unique

Every patient is unique and has individual therapeutic needs. Merz strives to provide more good days to every patient by investigating novel and flexible neurotoxin treatment options. For patients with movement disorders associated with muscle spasms, such as blepharospasm and cervical dystonia, or with spasticity in the upper limbs after a stroke, individualized injection therapy with botulinum neurotoxin can mean a significant increase in quality of life.

Patient video: Karl´s story

Highest International Standard

Botulinum neurotoxin is the product of a very complex biotechnical process. Merz uses state-of-the-art technology in its dedicated facility in Dessau, meeting the highest international standards for biologic manufacturing.

Development Activities

At Merz, we are dedicated to the ongoing development of our botulinum neurotoxin platform, which is set apart by the outstanding features of our product and our many years of scientific experience in this area. Our research focuses on modifications of botulinum neurotoxin as well as the extension of indication areas, with the goal of improving the lives of even more patients around the world.

Neck of a woman with necklace

What is Dystonia?

Dystonia is a neurological movement disorder characterized by involuntary muscle spasms and abnormal postures. Recent epidemiological studies indicate that there are more than 500 000 people across Europe with some form of the disorder. Botulinum neurotoxin is the primary treatment for two common types of dystonia, spasmodic torticollis (also known as cervical dystonia) and blepharospasm.

arm with spasticity

What is Spasticity?

Spasticity occurs when part of the nervous system that controls muscle activity becomes damaged. The damage can arise from injury or a medical event such as a stroke. Overall, spasticity affects about 500,000 people in the United States and more than 12 million people throughout the world.

As part of the rehabilitation process following a stroke, physiotherapy, injections of botulinum neurotoxin into spastic muscles, occupational therapy, speech therapy, medication, psychological support, and professionals in community teams may be recommended to help a person cope with the symptoms of spasticity.

Jump for Dystonia

The non-profit organization Dystonia Europe organizes an awareness campaign called JUMP for Dystonia since October 2014. The goal of the campaign is to collect as many jumps as possible. By people sharing their photos through social media, Dystonia Europe spreads the word dystonia to the general public together with the information that it is a brain disorder, causes involuntary muscle contractions, affects millions worldwide. Special JUMP for Dystonia events were also initiated by Merz. In 2014, more than 400 Merz employees demonstrated their support for dystonia patients and took part in “Merz Jumps for Dystonia”. For every jumped employee, Merz donated 5 Euros to the patient organization Dystonia Europe.

Jump for dystonia